Compounds > N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide
Page last updated: 2024-09-05

N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide and pha 793887

N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide has been researched along with pha 793887 in 1 studies

Compound Research Comparison

Studies
(N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide)		Trials
(N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide)		Recent Studies (post-2010)
(N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide)		Studies
(pha 793887)		Trials
(pha 793887)		Recent Studies (post-2010) (pha 793887)
90714012

Protein Interaction Comparison

ProteinTaxonomyN-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide (IC50)pha 793887 (IC50)
Cyclin-T1Homo sapiens (human)0.138
Cyclin-dependent kinase 1Homo sapiens (human)0.06
Cyclin-dependent kinase 4Homo sapiens (human)0.062
G2/mitotic-specific cyclin-B1Homo sapiens (human)0.06
Cyclin-A2Homo sapiens (human)0.008
G1/S-specific cyclin-D1Homo sapiens (human)0.062
G1/S-specific cyclin-E1Homo sapiens (human)0.008
Cyclin-dependent kinase 2Homo sapiens (human)0.008
Glycogen synthase kinase-3 betaHomo sapiens (human)0.079
Cyclin-dependent kinase 7Homo sapiens (human)0.01
Cyclin-dependent kinase 9Homo sapiens (human)0.138
Cyclin-HHomo sapiens (human)0.01
Cyclin-A1Homo sapiens (human)0.008
Cyclin-dependent-like kinase 5 Homo sapiens (human)0.005
Cyclin-dependent kinase 5 activator 1Homo sapiens (human)0.005

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1

Other Studies

1 other study(ies) available for N-[4-(3-chloro-4-fluoroanilino)-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide and pha 793887

ArticleYear
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013